Journal Basic Info

  • Impact Factor: 2.709**
  • H-Index: 11 
  • ISSN: 2474-1663
  • DOI: 10.25107/2474-1663
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Hormone Therapy
  •  Carcinomas
  •  Leukemia
  •  Radiation Oncology
  •  Immunotherapy
  •  Paediatric Cancers
  •  Surgical Oncology
  •  Colon Cancer

Abstract

Citation: Clin Oncol. 2021;6(1):1862.DOI: 10.25107/2474-1663.1862

Plasmablastic Lymphoma: Case and Review of the Literature

Escudero Sánchez G*, Redondo Guijo A, Férnandez Galán MA, González Hurtado JA, López López R and Pardal De La Mano E

Department of Internal Medicine, Hospital Virgen Del Puerto, Plasencia, 10003 Cáceres, Spain

*Correspondance to: Escudero Sánchez G 

 PDF  Full Text Case Report | Open Access

Abstract:

Plasmablastic Lymphoma (PBL) is an uncommon and aggressive subtype of diffuse large B-cell lymphoma, diagnosed commonly in middle-aged male patients, and historically associated with HIV-positive patients, involving the oral cavity. It has recently been described in HIV-negative patients affecting other levels, such as the pleura, pericardium, etc. This entity is characterized by
having positive CD38 and CD138 receptors, characteristic of plasma cell disease, negative CD20 receptors and high proliferative index (high Ki67). An early diagnosis and initiation of treatment is important, since it significantly improves the bad prognosis. Initial treatment recommended is conventional chemotherapy (CHOP, cyclophosphamide, Adriamycin, vincristine and prednisone)
or more intensive chemotherapy (EPOCH, etoposide plus CHOP). New approaches to this lymphomas includes proteasome inhibitors (bortezomib) adding to conventional chemotherapy. We describe a clinical case of Plasmablastic lymphoma and review the literature.

Keywords:

Cite the Article:

Escudero Sánchez G, Redondo Guijo A, Férnandez Galán MA, González Hurtado JA, López López R, Pardal De La Mano E. Plasmablastic Lymphoma: Case and Review of the Literature. Clin Oncol. 2021;6:1862..

Search Our Journal

Journal Indexed In

Articles in PubMed

Metastatic Retroperitoneal Paraganglioma: Case Report and Review of the Literature
 PubMed  PMC  PDF  Full Text
LINGO-1 is a New Therapy Target and Biomarker for Ewing Sarcoma
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Outcome of Allogeneic Bone Marrow Transplantation for Acute Myeloid Leukemia Following Single Agent Induction with Hypomethylation
 PDF  Full Text
Pregnancy Associated Breast Cancer Prognosis and Outcome, Qatar Experience
 Abstract  PDF  Full Text
View More...