Journal Basic Info

  • Impact Factor: 2.709**
  • H-Index: 11 
  • ISSN: 2474-1663
  • DOI: 10.25107/2474-1663
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Targeted Therapy
  •  Immunotherapy
  •  Colorectal Cancer
  •  Gastrointestinal Cancer
  •  Central Nervous System Tumors
  •  Brain and Spinal Cord Cancer
  •  Carcinomas
  •  Thoracic Oncology

Abstract

Citation: Clin Oncol. 2018;3(1):1486.DOI: 10.25107/2474-1663.1486

Could Using of Ultrasonic Grading for Axillary Lymph Nodes Improve Management of Early Stage Breast Cancer?

Ehsan Soltani, Masoud Pezeshki Rad, Monavar Afzal Aghaei, Kamran Ghaffarzadegan, Bahram Memar, Ali Jangjoo and Ramesh Omranipour

Department of Oncology Research, Mashhad University of Medical Sciences, Iran
Surgical Oncologist, Cancer Institute, Tehran University of Medical Sciences, Iran
Department of Oncology Research, Mashhad University of Medical Sciences, Iran
Department of Epidemiology and Biostatistics, Mashhad University of Medical Sciences, Iran
Department of Pathology, Research and Education Department, Razavi Hospital, Iran
Department of Oncology Research, Mashhad University of Medical Sciences, Iran
Department of Oncology Research, Mashhad University of Medical Sciences, Iran
Department of Oncology Research, Tehran University of Medical Sciences, Iran

*Correspondance to: Ramesh Omranipour 

 PDF  Full Text Research Article | Open Access

Abstract:

Purpose: Nowadays several studies suggested that needle biopsy of axillary suspicious nodes is more accessible than Sentinel Lymph Node Biopsy (SLNB); and thus, it is financially more beneficial. In this study, we compared using ultrasonographic features of lymph nodes alone, core needle biopsy, and SLNB for staging early breast cancers.
Methods: Participants included 50 patients who underwent axillary Ultra Sound-Guided Core Needle Biopsy (USG-CNB) from node/s larger than 10 millimeter (mm). Without considering the results of needle biopsy, SLNB, and if necessary axillary dissection were performed in all patients and the final results were compared.
Results: In all 38 (76%) cases with positive SLNB, final histology reports confirmed the diagnosis. In 24 of these patients, metastasis was diagnosed preoperatively by USG-CNB. Although only in 4 out 12 patients with normal lymph node characteristic in ultrasound, final histology revealed no metastasis. In patients with intermediate or suspicious feature, the test accuracy was more reliable. The total positive and negative predictive value of lymph node characteristic in ultrasonography were 95.7% and 40.7%, respectively.
Conclusion: Although ultrasonographic features of normal and metastatic lymph nodes can be helpful in accurate diagnosis of them, the accuracy of this modality alone is not enough to manage cancer patients with early stage breast cancer.

Keywords:

Early Detection of Cancer; Breast Neoplasms; Axilla; Neoplasm Staging; Needle Biopsy; Lymph Nodes; Ultrasonography

Cite the Article:

Soltani E, Rad MP, Aghaei MA, Ghaffarzadegan K, Memar B, Jangjoo A, et al. Could Using of Ultrasonic Grading for Axillary Lymph Nodes Improve Management of Early Stage Breast Cancer? Clin Oncol. 2018; 3: 1486.

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