Primary Lymphoma of the Sacrum- A Rare Entity

Amol Dilip Amonkar, Boney Perumal, Bhaskar Mallaiah, Fayiza Musthafa

Department of Lymphoma, KIMS Hospital and Research Centre, Bengaluru, India

^*Correspondance to: Bhaskar Mallaiah 

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Abstract:

Primary lymphomas of the bone are rare neoplasm accounting for approximately 0.4% of all primary bone tumours. We report a case of 39 year old male who presented with lower backache. Computed Tomography (CT) showed a mixed sclerotic and osteolytic lesion involving predominantly the right half of sacrum with adjacent soft tissue and muscle thickening and enlarged regional lymph nodes, mimicking a sacral neoplasm. Histology of the lymph node showed features of non-Hodgkins lymphoma, immunohistochemistry confirmed the diagnosis. The patient underwent radiotherapy followed by chemotherapy (CHOP Regimen). A diagnosis of primary lymphoma of the sacrum was made as it fulfils the criteria of primary lymphoma of the bone (PBL) that is involvement of a single skeletal site with or without regional lymph node involvement. To the best of our knowledge, primary lymphoma of the sacrum is an extremely rare condition and only a handful of cases are reported till date. We report a case of primary lymphoma of the sacrum with relevant discussion on the same.

Keywords:

Primary bone lymphoma; Non-Hodgkins lymphoma; Sacrum; Diffuse large B cell lymphoma; Immunohistochemistry

Cite the Article:

Amonkar AD, Perumal B, Mallaiah B, Musthafa F. Primary Lymphoma of the Sacrum- A Rare Entity. Clin Oncol. 2017; 2: 1273.