Journal Basic Info
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.Major Scope
- Chemoprevention
- Lymphoma
- Cervical Cancer
- Blood Cancer
- Brain and Spinal Cord Cancer
- Radiation Oncology
- Leukemia
- Central Nervous System Tumors
Abstract
Citation: Clin Oncol. 2017;2(1):1199.DOI: 10.25107/2474-1663.1199
B7 Gene Family: Promising Immunotherapeutic Checkpoint in Cancers
Yinxin Zhu, Jing Shen and Zhangang Xiao
Department of Gastroenterology, Soochow University, China
Department of Pharmacology, Southwest Medical University, China
*Correspondance to: Zhangang Xiao
PDF Full Text Short Communication | Open Access
Abstract:
The B7 gene family plays critical roles in regulating adaptive cellular immunity by either costimulating or co-inhibiting T cell functions. And the oncogenic roles of B7 family have already been identified in various cancers, with the immune checkpoint inhibitors of PD-L1/PD-1and CTLA-4/B7 being successfully applied in cancer treatment.
Keywords:
Cite the Article:
Zhu Y, Shen J, Xiao Z. B7 Gene Family: Promising Immunotherapeutic Checkpoint in Cancers. Clin Oncol. 2017; 2: 1199.
