Relevance of Repeat Transurethral Resection of the Bladder for High Grade pTa Bladder Cancer: A Review

Priscilla Leon, Adnan EL Bakri, Fan Cheng and Stéphane Larré

Department of Urology, Reims University, France
Department of Urology, Renmin Hospital of Wuhan University, China
Department of Urology, Tenon Hospital, France

^*Correspondance to: St�phane Larr� 

 PDF  Full Text Review Article | Open Access

Abstract:

Repeat transurethral resection of the bladder (reTUR) is highly recommended for high risk non muscle invasive bladder cancer. The evidence are strong for high grade pT1 tumors, but scarce for high grade pTa. In this systematic pubmed review, we analyzed the performance of reTUR for high grade pTa bladder cancer in terms of rate and characteristics of residual tumors. Data on survival was also retrieved and we provided meta-analysis figures on what to expect with such approach. ReTUR retrieved residual tumors in about half of the cases with upstaging to muscle invasive disease in almost 2%. Data were nonetheless insufficient to state on the relevance of reTUR high grade pTa. Based on analyzed data, we suggest to offer systematic reTUR for incomplete or muscle lacking initial TUR. For other high grade pTa tumors, a second look TUR shall be an option to be discussed at MDT meeting, based on the use of HAL or NBI at first TUR, the experience of the surgeon, and whether the patient would be fit for a close surveillance or additional treatments.

Keywords:

Urinary bladder neoplasms; Second-look surgery; Neoplasm; Residual; Repeat resection; Transurethral resection of the bladder

Cite the Article:

Leon P, EL Bakri A, Cheng F, Larré S. Relevance of Repeat Transurethral Resection of the Bladder for High Grade pTa Bladder Cancer: A Review. Clin Oncol. 2016; 1: 1115.