March, 2017


Research Article

Single Ablative Intravesical Electromotive Mitomycin C Administration for Small Non-Muscle-Invasive Bladder Cancer: A Prospective Study

Aim: To explore the effect of Electromotive Drug Administration Of Mitomycin C (EMDA-MMC) using a single dose of intravesical mitomycin C (MMC) to avoid transurethral resection (TURBT) for small non-muscle-invasive bladder cancer.

Published 31 Mar, 2017


Editorial

99mTc-MDM SPECT Offers ‘Standard of Diagnostic Care’ in the Management of Glioma

Glioblastoma Multiforme (GBM) is the most common primary brain tumor in adults.

Published 31 Mar, 2017


Editorial

The End Results of the Treatments, Depend on the Total Therapy and Effectiveness of the Planned and the Given Such Treatments

In the news, that even the treatment options for laryngeal cancer patients seemed to be improved, but survival rates did not.

Published 31 Mar, 2017


Case Report

Benefits of Metastasectomy in Esophagogastric Cancer

Background: Esophagogastric cancer is the second most common cause of cancer related deaths worldwide and often presents late with approximately 32% of US patients presenting with distant metastases.

Published 30 Mar, 2017


Mini Review

Lu-177 - A Noble Tracer: Future of Personalized Radionuclide Therapy

Radionuclide therapy using radiopharmaceuticals is in existence for over sixty years. Iodine-131 remains the work-horse for the treatment of thyroid cancer due its efficacy and ease of administration.

Published 24 Mar, 2017


Research Article

Multi-Professional Follow-Up Programmes are Needed to Address Psychosocial, Neurocognitive and Educational Issues in Children with Brain Tumours

Aim: The aim of this study was to coordinate the structured psychosocial, neurocognitive and educational follow up of children treated for brain tumours with the medical protocol and apply the model in two Swedish healthcare regions.

Published 24 Mar, 2017


Review Article

EGFR Targeting in Oesophageal Squamous Cell Carcinoma: Potential Role and Rationale

Oesophageal cancer remains a highly lethal malignancy in spite of advances in multimodal approaches that have been adopted in its management during the last two decades.

Published 24 Mar, 2017


Research Article

The Effect of Corticosteroid Eye Drops on the Prevention of Eye Disorders Caused by High-Dose Cytarabine Therapy

Side effects of high-dose cytarabine (HDCA) treatment include cytarabine syndrome with symptoms such as fever, muscle pain, and conjunctivitis.

Published 24 Mar, 2017


Review Article

Breast Cancer Biomarker Changes after Neoadjuvant Chemotherapy: A Single Institution Experience and Literature Review

Chemotherapy and hormonal treatment decisions for breast cancer are influenced by the expression of tumor biomarkers, including estrogen receptor, progesterone receptor and human epidermal growth hormone receptor 2 (HER2/neu).

Published 23 Mar, 2017


Review Article

Rising Incidence of Allergy and a Topic Disorders and Hygiene Hypothesis

An important contribution to understanding the causes of the increasing incidence of allergic, atopic and other immunopathological conditions in the pediatric population and, later on increased incidence of non-communicable diseases (eg., Type 2 diabetes, and autoimmune diseases) in adulthood was the hygiene hypothesis.

Published 23 Mar, 2017


Research Article

Feasibility of a Fast-Track Cystectomy Program

Introduction: Enhanced Recovery After Surgery (ERAS) has consistently led to decreased need for hospitalisation and risk of complications without increased readmission rates.

Published 23 Mar, 2017


Review Article

Personalized Therapy for Pancreatic Cancer: Challenges and Opportunities

Pancreatic Ductal Adenocarcinoma (PDAC) has one of the lowest 5-year survival rates of all cancers.

Published 22 Mar, 2017


Research Article

The Evaluation of Dyspnea in Elderly Patients with Advanced Non-Small-Cell-Lung Cancer Receiving Palliative Chemotherapy

Background: Therapeutic decisions in lung cancer patients are in great part based on ECOG performance status.

Published 22 Mar, 2017


Short Communication

The Link between Increased Body Mass Index and Radiotherapy of Childhood Leukemia: The Need to Manage Obesity in Pediatric Leukemia Patients

Although radiotherapy is one of the most important modalities used to cure cancer, radiation exposure can damage the human body.

Published 22 Mar, 2017


Commentary

Promises: Alternative Medicine in the Era of Innovative Cancer Therapy

Tumorigenesis evolves following a doctrine that is as much stochastic as it is Darwinian in nature.

Published 22 Mar, 2017


Short Communication

Advancement of the Technology in Radiation Oncology

Today, approximately 120 years after the discovery of X-Ray, November 8, 1895 by German physicist Wilhelm Conrad Röntgen, radiation therapy has taken a gaint leap and has become not only very advanced and sophisticated but also precise and conformal.

Published 22 Mar, 2017


Research Article

Clinical Outcomes of Adjuvant Therapies in Early Stage Invasive Cervical Cancer: More Research is Needed

Introduction: Uterine cervical cancer is one of the most common malignancies worldwide and the second most common gynecological cancer, specifically within the age group of 55–59 years.

Published 22 Mar, 2017


Mini Review

The Role of the Insulin Receptor is Forms in the Insulin- Like Growth Factor Signaling Axis in Cancer

The Insulin-like Growth Factor (IGF) signaling system is known for regulating critical cellular processes related to growth and apoptosis.

Published 21 Mar, 2017


Case Report

The WHO Classification 2016 of Tumours in the Urinary System and Male Genital Organs and Impact on the Bladder Cancer

12 years after the previous WHO, a new WHO classification was published in January 2016 (1).

Published 21 Mar, 2017


Short Commutation

The Importance of Individualized Prognostic Indicators

Once initial diagnosis is made, key to adequate cancer treatment is prognosis determination.

Published 21 Mar, 2017


Commentary

Recent Molecular Immunological Chemotherapy for Gastrointestinal Malignancies

Efficacy of anticancer agents is generally dose-dependent and thus is determined by the Maximum Tolerated Dose (MTD) and Dose-Limiting Toxicities (DLT).

Published 21 Mar, 2017


Short Communication

Values for a Successful Research & for Researchers

Researchers in science and medical fields have been examining many aspects of life, including illnesses and diseases.

Published 20 Mar, 2017


Case Report

Metastatic Soft Tissue Sarcomas in Elderly Patients: 18 Years of Monoinstitutional Experience

Elderly people represent more than 50% of sarcoma patients, but very few data are available on the results of treatment of this population.

Published 20 Mar, 2017


Review Article

Postoperative Radioactive Iodine for Differentiated Thyroid Cancer: A Historical Perspective

Radioactive iodine has been used in differentiated thyroid cancer for postoperative thyroid remnant ablation for several decades, yet its indications remain controversial.

Published 20 Mar, 2017


Short Communication

Palliation of Extra-Hepatic Biliary Malignancies: Diminishing Role for Surgery

In a recently published manuscript, Buettner and colleagues [1] provides an analysis of outcomes following palliative surgery for extra hepatic biliary malignancies over a period of 15 years from ten of the best cancer centres in the United States.

Published 20 Mar, 2017


Research Article

Response-Based Intensive Induction Chemotherapy of Curative Approach in Elderly Acute Myelogenous Leukemia Patients in Single Institution

To date, about 60-80% of adults with previously untreated de novo Acute Myeloid Leukemia (AML) enter Complete Remission (CR) when treated with standard regimen.

Published 20 Mar, 2017


Short Communication

Eating Right to Block Left Premalignant Lesion of GI Cancers

Prof. WK Hong and prof. MB Sporn in their publication at "Science" journal [1] defined chemoprevention as cancer prevention using pharmacologic or natural agents that inhibit the development of invasive cancer either by blocking the DNA damage or by reversing the progression of premalignant cells.

Published 20 Mar, 2017


Case Report

Primary Breast Sarcoma: A Case Report

Breast cancer is the commonest cancer that afflicts females worldwide. Of all the cancers of the breast majority arise from epithelial component (carcinoma).

Published 20 Mar, 2017


Review Article

The Impact of Climate Change on Paediatric Oncology

Background: According to some experts, climate change will be the greatest health-related hazard in the 21st century.

Published 17 Mar, 2017


Short Communication

Trends of Molecular Research for Pancreatic Cancer Diagnostics: Insights of Clinician

Pancreatic cancer is an aggressive malignancy with very high negative impact for overall patients survival and non-reducing incidence rates in western countries [1,2].

Published 17 Mar, 2017


Case Report

A Young Patient with Mantle Cell Lymphoma has been Cured by Myeloablative Hematopoietic Stem Cell Transplantation

The diagnosis of Mantle Cell Lymphoma (MCL) is rarely made in young adults as the disease is most commonly encountered in middle age and elderly individuals.

Published 17 Mar, 2017


Research Article

Role of 18F-FDG PET/CT in Gastric Carcinomas: Comparison with Contrastenhancement Computed Tomography

Purpose: The purpose of this study was to investigate the usefulness of 18fluorodeoxyglucose Positron Emission Tomography /Computed Tomography (18F-FDG PET/CT) in patients with gastric carcinoma and to compare it with contrast enhancement CT.

Published 17 Mar, 2017


Mini Review

Malignant Transformation Potential of Dysembryoplastic Neuroepithelial Tumors

Dysembryoplastic neuroepithelial tumorisa relatively recently recognizedneuropathological entity that was first proposed in 1988.

Published 17 Mar, 2017


Research Article

Renal Cell Carcinoma with Level IV Cavo-Atrial Thrombus: Short Term and Long Term Outcomes

Introduction: With the technological advances surgical treatment of Renal Cell Carcinoma with a level IV Cavo-Atrial Thrombus is now feasible, and the thrombus can almost always be removed successfully.

Published 16 Mar, 2017


Mini Review

Choline PET/CT Imaging for Management of Prostate Cancer

Whole-body Positron Emission Tomography/Computed Tomography (PET/CT) with [11C]- and [18F]-labeled choline derivatives has emerged as a promising molecular imaging modality for evaluation of prostate cancer.

Published 16 Mar, 2017


Mini Review

The Role of Meningioma-1 (Mn1) Gene as Marker for Prognosis and Minimal Residual Disease Monitoring in Acute Myeloid Leukemia: A Concise Review

Molecular markers are necessary for prognostic stratification and monitoring of Minimal Residual Disease (MRD) in Acute Myeloid Leukemia (AML) [1,2].

Published 13 Mar, 2017


Editorial

Management of the Positive Axilla in 2017

Almost 100 years ago routine removal of the axillary nodes in what is known as an Axillary Dissection (AD) became part of the standard surgical treatment of breast cancer after publication of the autopsy studies performed by the German pathologist Rudolf Virchow’s (1821-1902).

Published 13 Mar, 2017


Case Presentation

Rare Breast Myoepithelial Carcinoma with a Distinctive Genetic Profiling Study

We describe a 74-year-old woman with no family history of breast cancer who presented with a high-grade myoepithelial carcinoma.

Published 13 Mar, 2017


Review Article

Lymphoma and the Cranial Nerves

Enlargement of peripheral nerves is unspecific and can occur in inflammation, different types of nerve tumors and in malignancies.

Published 03 Mar, 2017





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