April, 2017


Case Report

Effects and Side Effects of Nivolumab: From Pneumonitis to Complete Remission Complete Response of Metastatic NSCLC after Resolution of a Pneumonitis on Nivolumab Treatment

Non-Small Cell Lung Cancer (NSCLC) without driver mutations has limited the rapeutic options beyond first line chemo therapy.

Published 01 May, 2017


Case Report

Two Patients with Advance-Stage Renal Cell Carcinoma Developed Sunitinib-Related Skin Toxicity

With the current treatment modalities like molecular targeted therapy, general survival rates have increased in patients with advanced-stage renal cell carcinoma.

Published 26 Apr, 2017


Research Article

Physical, Emotional and Spiritual Well-Being, Dignity and Hope in Adult Patients with Solid and Hematologic Malignancies, on Cure or Follow-Up

Introduction: In oncological setting, the assessment of physical/emotional symptoms and above all of existential/religious needs and resources, hope and dignity are rarely performed in the routine clinical practice.

Published 26 Apr, 2017


Research Article

Improved Utilization of Resources as an Improvement of Outcome: the Effect of Multidisciplinary Team for Rectal Cancer in a District Hospital

Aim: Today, treatment decisions about patients with rectal cancer are increasingly made within the context of a Multi-Disciplinary Team (MDT) meeting.

Published 26 Apr, 2017


Case Report

Acute Esophageal Necrosis Complicated by Severe Upper Gastrointestinal Bleeding in Association with Bosutinib Treatment for Chronic Myelogenous Leukemia

Acute Esophageal Necrosis (AEN), also known as “Black Esophagus”, is a rare life threatening condition with unknown cause.

Published 26 Apr, 2017


Review Article

Circulating Tumor DNA as a Liquid Biopsy in Cancer

Circulating tumor DNA represents a promising biomarker for non-invasive assessment of cancer progression and evolution.

Published 24 Apr, 2017


Editorial

Hereditary Colon Cancer Syndromes: Optimal Management in 2017

Colorectal Cancer (CRC) is the third most common cancer in the United States [1]. Almost onethird of the cases show familiar predisposition and a genetic syndrome is identified in approximately 5% of newly diagnosed patients [2].

Published 24 Apr, 2017


Editorial

Sunscreen- The Double Edged Sword

Sunscreens have long being recognized as substances to provide effective protection against the detrimental effects of solar radiation.

Published 14 Apr, 2017


Case Report

Lipofibromatosis of the Paravertebral Soft Tissue in a Child of Two Years Old

Lipofibromatosis is a bland fibroproliferative process that invades skeletal muscle. Typically the children are affected before 8 years with a peak under 2 years old.

Published 14 Apr, 2017


Mini Review

Genetic Characterization of Choriocarcinoma and Potential Clinical Implications

Choriocarcinoma is a unique neoplasm that can occur after a pregnancy, as a component of germ cell tumors, or follow the trophoblastic differentiation of neoplastic somatic cells that completely lose their normal phenotype and produce hCG.

Published 07 Apr, 2017


Mini Review

Nuclear Scanning in Evaluation and Treatment of Thyroid Disorders: A Beginners Guide

Thyroid disorders are common worldwide and the biggest fear amongst most patients with neck swellings is thyroid cancer.

Published 04 Apr, 2017


Research Article

Long Term Follow-Up in Children Undergoing Nephron Sparing Surgery for Non-Syndromic Unilateral Wilms Tumor

Introduction: Wilms Tumor (WT) represents approximately six to seven percent of all pediatric cancers and accounts for more than 95 percent of all tumors of the kidney in the pediatric age group.

Published 03 Apr, 2017


Research Article

Evaluation of Adverse Events in Dogs with Adenoviral Therapy by Intralymphonodal Administration in Canine Spontaneous Multicentric Lymphosarcoma

Background: Therapy administration in cancer is mainly performed by intravenous, oral, and in situ routes.

Published 03 Apr, 2017


Case Report

Lung Cancer Lymphatic Drainage and Bilateral Lung Transplantation

A 25-year-old female patient with cystic fibrosis underwent bilateral lung transplantation.

Published 03 Apr, 2017


Editorial

ZEB1 is an Oncogenic Factor that Represses Many Tumor Suppressorsin Uveal Melanoma

Uveal Melanoma (UM) is the most common intraocular tumor in adults, with an incidence rate of 4.3 per million in USA [1,2].

Published 03 Apr, 2017


Editorial

Tumor Heterogeneity and Its Clinical Significance

The tumor of human body, especially malignant tumor, is composed of cells with different pathological and biological behavior.

Published 03 Apr, 2017


Research Article

Assessment of Low Dose Vigil® Engineered Autologous Tumor Cell (EATC) Immunotherapy in Patients with Advanced Solid Tumors

Previously we demonstrated not only safety but alsoprovided evidence of clinical benefit to Vigil® vaccine(1 x 107cells/injection 1x/month for 1-8 injections).

Published 03 Apr, 2017





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